Damian: Co-chair of the Student Activities Committee and Janis’s best friend. Damian is smart, witty, and confident and occasionally serves as the show’s narrator.

Gender: male

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Janis Sarkisian: Marches to the beat of her own drum and, with Damian, narrates throughout the show. After a falling-out with Regina in middle school, she became a bit of a social outcast and still holds a grudge against Regina. Damian is her best friend and lovingly refers to her as his “art freak.” 

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Cady Heron: Arrives at North Shore High a clueless transfer student but is quickly wrapped up in brutal social politics. Though at her core Cady is levelheaded, self-assured, and kind, when she goes undercover with the Plastics, she becomes unrecognizable. 

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Ms. Norbury: Cady’s homeroom and calculus teacher, and she oversees the Mathletes. Though she is a bit jaded and more than a little sarcastic, Ms. Norbury sees the real Cady and encourages her to be true to herself.

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Regina George:The undisputed Queen Bee of North Shore High School, and she knows
it. She’s confident, clever, and completely unbothered by anyone else’s opinion. While Regina purposefully manipulates everyone around her (including her own mom), at her heart, she’s trying to fit in, just like everyone else. 

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Gretchen Wieners: Regina’s stressed-out second-in-command. As much as Regina appears not to care what people think, Gretchen cares very much, and she’s especially paranoid when it comes to Regina. She takes the Plastics very seriously and is completely controlled by Regina, until Cady comes along. 

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Karen Smith: The third member of the Plastics. While Karen’s lack of intelligence is a running joke throughout the show, she sees the other girls more clearly than most people and is the most laid back of the three. 

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Aaron Samuels: A nice guy who has no idea that he’s the high school heartthrob. Although he doesn’t enjoy the drama of high school social politics, he gets used as a pawn between Cady and Regina, though he genuinely likes Cady.

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Mrs. Heron and Mr. Heron: Cady's parents.

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Mr. Duvall: The school principal. Like Ms. Norbury, he’s seen it all, although he’s slightly more formal and sincere than Ms. Norbury’s sarcasm.

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Shane Oman

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Kevin G: Captain of the Mathletes! He’s confident and excited about competing with the team, and he’s proud of their accomplishments. 

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Martin: Kevin G's second in command.

 

Mrs. George: Desperate to be a "cool mom".

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Ensemble

Party Guests, the Debate Team, Dance Team, Show Choir, Mathletes, and Students. Cast Taylor, Caitlyn, Rachel, Caroline Krafft, Tony, Marymount Captain, Teary Girl, Mathletes Moderater Sonja Acquino, Glenn Cocco, Dawn, Grace, Lizzie, Sophie, and Jason